A while ago I gave one of our bankers a bottle of CBD Oil containing 500 mg of CBD.
I heard nothing for a few weeks because, instead of using it himself, he gave it to a close relative. This relative suffered from Crohn’s disease and he wondered if it would help. He heard nothing good for three weeks but then he got a call that the product was really helping his relative feel well and normal. They were thrilled and said it was a “life changer”. He was thrilled also and thanked us profusely. He also ordered another bottle.
It is stories like these that keep Rob, Janice and I slogging away trying to reach as many people as we can about the miraculous effects that CBD can have on ailing people.
The testimony inspired me to look for studies on why CBD helps Crohn’s sufferers and found in pubmed.gov a placebo controlled study stating that “cannabis produces significant clinical benefits in patients with Crohn’s disease”. Although the mechanism isn’t quite clear yet, they suspected the CB1 and CB2 receptors played a major role in easing symptoms. The study mentioned that these results backed up the many anecdotal claims about the effectiveness of Cannabis in treating bowel and gastro conditions.
Looking for further information into what mechanisms can generate such positive results I found a more precise explanation in a presentation by Dr. Jeffrey Hergenrather’s at the CME course accredited by UCSF, MMJ13001A and B. With the help Mark Ware, MD, of the Alan Edwards Pain Management Unit, McGill University on the body’s cannabinoid signaling system, Hergenrather displayed and discussed slides showing the cannabinoid receptors throughout the bowel wall and the general focus of the presentation led to 2 key statements about the mechanisms responsible for such positive results:
- Activating the CB1 receptor, down-regulates intestinal motility and intestinal secretions while decreasing inflammation, pain and the risk of tumors.
- Activating the CB2 receptor decreases visceral pain and inflammation, and also down-regulates intestinal motility.
“This has a huge effect on patients with Crohn’s disease” said Hergenrather.
See their attached illustration for more information.
In conclusion: CBD Oil does a great job in activating the bodies ECS (Endocannabinoid System) receptors of which CB1 and CB2 are the most important.
Finishing up his presentation, Hergenrather veered off topic and talked of other conditions. He concluded “Over the course of several years, we, collectively, did not see any significant adverse effects associated with cannabis through gestation and nursing.” Also, “It works better than anything for morning sickness.” Nevertheless, he advised the doctors to “advise judicious use during pregnancy.”
Hergenrather also extolled the potential of cannabinoids in treating certain types of cancer. Although the CME presentation was not planned to have a focus on cannabinoids in the treatment of cancer, Hergenrather concluded by extolling its potential.
“I’ve been encouraging patients to make the oil and put it directly on skin lesions,” he said. “If I thought someone had a melanoma I would hustle them to the surgeon. But for just about any other kind of skin lesion, ‘Put the cannabis oil on it and watch the results.’”
So if you are willing to try new things, a multi-functional, non-psychoactive, legal in all 50 states, CBD Oil could be a good start to feeling better.